Depending on individual circumstances, DenSureFit users in different stages change out their liners more or less frequently.
DenSureFit is a temporary solution for loose dentures and should be used to make the denture fit correctly in between regular adjustments from the dentist. The average amount of time that people tend to leave their liner in before replacing it is around 3 months. This varies between people, so some go longer and some less.
New denture wearers may have to change their liner more frequently because of rapidly changing gums. Established wearers may be able to wear it for much longer.
It is important to keep the liner bacteria-free by removing the denture nightly and soaking it in a denture cleanser like you normally probably already do. As long as the liner/denture is being kept bacteria-free and it is in good condition and fitting well, keep it in. If it starts to show signs of wear, change it out. If it is in good condition but your denture loosen, add more silicone on top of your previous layer following the Snug-Up directions in the booklet.